It would be the Pure food and Drug Act. The main purpose of the Pure Food and Drug Act of 1906 was to ban foreign and interstate traffic in adulterated or mislabeled food and drug products, it led to the creation of the Food and Drug Administration (FDA). The Dawes Act of 1887 authorized the President of the United States to survey American Indian tribal land and divide it into allotments for individual Indians. Those who accepted allotments and lived separately from the tribe would be granted United States citizenship. There is no such thing as The Federal Medication Act or the Federal Drug Administration.
The Founding Fathers knew that in the upcoming future with the changing time, there would be a need of change in the US government that would stand for the upcoming generations.
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The affirmation of Independence had a presumption that people possesses a Right of Revolution. So in order to avoid any riot, they included amendment that offered a method to pursuit the Right of Revolution without any resort to arms and initiated the power in order to change the Constitution to the place it belongs to with the people. The Founding Fathers made the amendment procedure difficult to achieve because to look in the political leads which created the ratification of the constitution. They believed and recognized that the 'ground rules' should be constant in order for a government to function well.
It was John Tyler.
Tyler's opponents regularly called him "His Accidency" and addressed correspondences to him as "Vice President" or "Acting President" (letters which he returned unopened).
When his term ended in 1845, he did not seek election.
A. Unrestricted Submarine Warfare.
This caused Germans to attack vessels that carried US citizens, bringing the US into the war.