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Gene knockout is a technique used to determine the function of a gene that has already been sequenced, which is achieved by analyzing the phenotype of the individual carrying the knockout mutation(s). Moreover, gene sequencing is a technique used to determine the sequence of a given gene, which allows to determine how gene variants (polymorphisms) may be associated with the phenotypes of the target trait.
Explanation:
In genetics, gene knockout is a technique used to trigger mutations in a (already) sequenced gene in order to inactive its function and observe the resulting phenotype for a particular trait. This approach that starts with the inactivation of a given gene and ends with the phenotype is known as reverse-genetics. On the other hand, gene sequencing can be defined as the methodologies/techniques/tools used to determine the nucleotide base pair sequence of a particular gene. The gene knockout technique involves knowing a priori the gene sequence in order to obtain a gene knockout (gene KO). The combination of the information obtained from these techniques can be used to determine how variation (genetic variation) affects the expression of a phenotypic trait.
<span>The number of protons plus the number of neutrons is called the mass number.</span>
Let us look at the what, why and how of studying extreme places like the deep earth and the deep space. Scientists need to figure out as to 'what' they want to look at such places, be it a new exotic creature or bio-genesis (birth of life). Unless there are several testable hypothesis constructed, such a study cannot begin. The 'why' aspect deals with the purpose of such research and expeditions. Is it of any use to the humans, or will it improve our current understanding of a phenomenon? The 'how' aspect deals with the technology and the economic assistance that can help in undertaking such a research. All these are the challenges that needed to be thoroughly considered to make such a research or expedition possible.
White blood cells produce antibodies which fight off the pathogens
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