Option 1 is the correct answer.
Answer:
Explanation:
This is because sickle cell disease is common in malaria dorminated area because their traits confers resistance to malaria. The red blood cells, which contain abnormal hemoglobin become sickle in shape after it has been affected by malaria parasite. Therefore, most American that have African ancestry are at high risk of
the disease because the African ancestry are carriers if this gene and are inherited by the Americans.
Answer:b. One of the most significant environmental issues is the large quantity of waste produced by businesses and society.
Explanation:
A pollution is a drawback for the development of the environment. The pollution is produced by the liberation of toxic chemicals, agents or even sound at high volume. It disturbs the natural balance of nature. The pollution can be caused by the liberation of toxic wastes from the production businesses and societies. This causes harm to the society by deteriorating the natural environment.
Answer:
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Explanation: shgygsvmcngdfwjheagf
Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
