It’s the study of people and the outside world
Answer:
Mechanisms are activated where it is sought to lower the amount of free protons in the blood, that is, to reduce acidity, these mechanisms work between two large systems, the receptor system, the respiratory system and the renal system.
Explanation:
When a metabolic acidosis is entered, either by a food, or by a disease or even an intense physical activity, the lungs seek to generate hyperventilation, to increase the concentrations of oxygen in plasma and absolutely decrease the carbon dioxide concentration, thus not the blood becomes even more acidic.
On the other hand, the digestive system together with the sensory system, will warn this proprioception of the acidity of the plasma and will promote the dilution of these acids with a solvent, which is water, promoting the sensation of thirst.
Finally, the kidneys will seek to retain all the alkaline solutes to neutralize the physiological internal pH, and will release through the urine and the channels of acidic compounds, the products or acid metabolites to the external environment, that is, acid urine excretion.
Basic charged atomic particles are electrons (negatively charged) and protons (positively charged). It is a particle on an atomic scale that is charged
Answer:
Results
We systematically analyze and compare how different modelling methodologies can be used to describe translation. We define various statistically equivalent codon-based simulation algorithms and analyze the importance of the update rule in determining the steady state, an aspect often neglected. Then a novel probabilistic Boolean network (PBN) model is proposed for modelling translation, which enjoys an exact numerical solution. This solution matches those of numerical simulation from other methods and acts as a complementary tool to analytical approximations and simulations. The advantages and limitations of various codon-based models are compared, and illustrated by examples with real biological complexities such as slow codons, premature termination and feedback regulation. Our studies reveal that while different models gives broadly similiar trends in many cases, important differences also arise and can be clearly seen, in the dependence of the translation rate on different parameters. Furthermore, the update rule affects the steady state solution.
Conclusions
The codon-based models are based on different levels of abstraction. Our analysis suggests that a multiple model approach to understanding translation allows one to ascertain which aspects of the conclusions are robust with respect to the choice of modelling methodology, and when (and why) important differences may arise. This approach also allows for an optimal use of analysis tools, which is especially important when additional complexities or regulatory mechanisms are included. This approach can provide a robust platform for dissecting translation, and results in an improved predictive framework for applications in systems and synthetic biology.
hope it help friends
Choice #1 & Choice#4 I believe
