Question

An adult client underwent diagnostic testing after experiencing an absence seizure for the first time. What aspect of this client’s health history may result in impaired drug excretion?

Answer 1

Answer: The history of client's renal function may impact drug excretion. It also includes smoking history of client, hepatic blood flow and use of drugs.

Explanation:

The excretion of drug from a client's body is effected by the fact that how his kidney functions, that is renal function.

If a person smokes then it impacts excretion of drug.

Patients with history of heart failure and decreased hepatic blood flow have impaired drug excretion.

Intake of certain drugs that induce or restrain cytochrome P-450 metabolic enzymes also results in impaired excretion of drug.

Other factors that affect the excretion includes : protein binding , urine flow and PH of urine.