Question

The enzyme phosphofructokinase (PFK) catalyzes a key step in glycolysis. About 10% of Springer spaniels suffer from canine PFK deficiency. Given its critical role in glycolysis, which of the following conditions would be a likely consequence for dogs afflicted with this disorder?
They would be lethargic and readily tire from exercise.

Answer 1

Answer:

The correct answer is that they would be lethargic and readily tire from exercise.

Explanation:

In glycolysis, the Phosphofructokinase (PFK) catalyzes the ATP-dependent phosphorylation to convert fructose-6-phosphate into fructose 1,6-bisphosphate and ADP.  it is one of the key regulatory of glycolysis which helps in producing energy. A PFK deficiency would make the afflicted dogs to  be lethargic and readily tire from exercise. This is because little or no energy is produced in the body.