Answer:
C. The enzyme with mutation 1 has decreased affinity for pyridoxal phosphate, whereas the enzyme with mutation 2 has lost the ability to bind to the substrates.
Explanation:
A coenzyme is an organic cofactor that binds with an enzyme in order to initiate or aid the function of the enzyme. A coenzyme binds to the active site of the enzyme (where the reaction occurs), thereby triggering its activation by modifying protein structure during the reaction. Some examples of coenzymes include Coenzyme A and Adenosine triphosphate (ATP). Pyridoxal phosphate is a coenzyme (it is the active form of vitamin B6) that is required for the function of cystathionase. Moreover, cystathionase is an enzyme that enables cells the synthesis of cysteine from methionine (transsulfuration pathway). The binding of pyridoxal phosphate to the enzyme increases the binding affinity of the enzyme for the substrate, thereby influencing its activity. In this case, it is expected that mutation 1 reduces the binding affinity of the enzyme to the cofactor, and thereby the cofactor is required at a higher concentration to restore normal enzyme activity.
Answer:
The average adult, when resting, inhales and exhales about 7 or 8 liters of air per minute. That totals about 11,000 liters of air per day. Inhaled air is about 20-percent oxygen. Exhaled air is about 15-percent oxygen.
Explanation:
If you want water to flow out of the tubing piece filled with a 50% solution, the minimum concentration of the solution in the beaker must be more than 50%. This is because, water can only flow out of the tubing piece if the concentration of the water inside the beaker is greater than that of the tubing piece; the water will move from the region of low concentration to the region of high concentration.
Answer:
Explanation:
doppler radar, radiosondes, weather satellites, buoys and other instruments are fed into computerized NWS numerical forecast models. The models use equations, along with new and past weather data, to provide forecast guidance to our meteorologists