Because the endocrine system has to release a hormone that is transferred though the blood stream it can take a few seconds or minutes before the message is received.
<span>The endocrine system has the advantage to send a message to multiple cells all over the body with less energy expense to your body. </span>
In the interphase, they are really thin, just one strand which is only a few atoms wide (very challenging for an optical microscope and not too easy for the electronic one)