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marta [7]
3 years ago
13

Para que ocurra la sintesis de colesterol la via glucolitica tiene que estar activa

Biology
1 answer:
Ronch [10]3 years ago
6 0

Answer:

el acetil-CoA necesario para la síntesis de colesterol puede provenir de la vía glucolítica

Explanation:

El colesterol es fundamental para la formación de las membranas celulares, actuando como mediador del grado de fluidez en las membranas; además, esta molécula actúa como precursor de hormonas esteroideas y ácidos biliares. La sintesís de colesterol empieza con la condensación de acetil-CoA y acetacetil-CoA:

Acetil-CoA + Acetacetil-CoA + H2O >>> 3-hidroxi-3-metil-glutaril-CoA

Ahora bien, el acetil-CoA para este proceso puede ser producido por la degradación hasta piruvato del excedente de glúcidos mediante de la vía glucolítica. Este reacción se produce dentro de la mitocondria, donde el piruvato produce acetil-CoA.

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