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ANEK [815]
3 years ago
11

Some autoimmune diseases show a positive correlation with dramatically decreased expression of histone deacetylase (HDAC9, an en

zyme that removes acetyl groups from histones). Why would the decreased expression of HDAC9 cause immune cells to produce inflammatory genes at inappropriate times?
Biology
1 answer:
soldier1979 [14.2K]3 years ago
6 0

Answer:

The positive charge of the histone proteins get reduced due to the process of histone acetylation, thus making the wrapping of DNA around the histones less tightened. The loose connected DNA afterward associates with the transcription factors for the articulation of the genes situated in that area.  

Generally, when there is no requirement of gene anymore, the acetyl groups from the histones get withdrawn by the activity of histone deacetylase enzyme (HDAC9) that makes the DNA tightly wrapped and inaccessible again. In case, when less expression of histone deacetylase enzyme occurs, the process of deacetylation fails to take place. This indicates that within an immune cell, at the time of infection, the inflammatory gene, which was made available does not get re-wrapped firmly around the histones.  

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Meselson and Stahl cultured E. coli for several generations in a medium with a heavy isotope of nitrogen, 15N. They transferred
Sidana [21]

Answer:

DNA replication follows semi conservative mode of replication

Explanation:

The results of Meselson and Stahl's experiments can be explained by semi conservative mode of DNA replication. According to it, the two DNA strands separate and both are used for synthesis of new DNA strands such that the new DNA molecule has one parental and one new strand.

In the experiment, originally the medium was 15N so all the DNA molecules had 15N. Later the medium was changed to 14N. In first round of replication in new medium, the two 15N strands in a DNA molecule separated and formed new strands using 14N. So all the DNA molecules had one 15N and one 14N strand.

In the second round of replication, the 15N-14N hybrid DNA molecule separated again. Now, 15N gave rise to 14N strand and 14N strand also gave rise to 14N strand such that half of the DNA molecules were 15N-14N hybrids and half were 14N-14N. Hence, researchers concluded that DNA replicated according to semi conservative mode of replication.

8 0
3 years ago
Bacterial species whose shape is variable or morphologically indistinct depending on environmental conditions is called ________
katovenus [111]

Answer:

The given blank can be filled with pleomorphic.

Explanation:

Pleomorphism, in microbiology, refers to the tendency of some of the microbes like bacteria to change their size or shape in response to the environmental conditions. In the context of bacteriology, pleomorphism is based upon the change in the shape or size of the cell, in spite of a change of shape as considered previously.

3 0
3 years ago
(01.02 HC) What inference can correctly be drawn from the diagram shown below? (2 points) Image depicts four very similar birds
stealth61 [152]
You can infer that the birds once had a common ancestor but became separated. Mutations in copying their genes stacked and caused changes in the beaks so the birds could be more well off or better adapted in their new environment.
4 0
3 years ago
Read 2 more answers
What is another name for an animal that is only a secondary consumer?
galben [10]
An animal that is only a secondary consumer can also be called a HERBIVORE
6 0
3 years ago
A particular cell has a mutation that causes it to make defective centromeres. What would you expect to occur during mitosis?
BigorU [14]

Answer:

The correct answer is D Sister Chromatids may not attach to each other.

Explanation:

Centromeres are the specific point to which the sister Chromatid binds.That means Centromere function to hold the sister Chromatids.

        Now according to the question if mutation causes formation of defective centromere then the normal functioning of that centromere will be hampered.

         As a result the sister chromatid may not attach to each other.

4 0
4 years ago
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