Examples of recessive diseases include cystic fibrosis and Tay-Sachs disease. Multifactorial inheritance disorders are caused by a combination of small inherited variations in genes, often acting together with environmental factors. Heart disease, diabetes, and most cancers are examples of such disorders.
Sweating: Your sweat glands release sweat, which cools your skin as it evaporates. This helps lower your internal temperature. Vasodilatation: The blood vessels under your skin get wider. This increases blood flow to your skin where it is cooler — away from your warm inner body.
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Answer:
E1: Pyruvate dehydrogenase, TPP, oxidative decarboxylation reaction
E2: Dihydrolipoyl transacetylase, Lipoamide and Co-enzyme A, transacetylation reaction.
E3: Dihydrolipoyl dehydrogenase, FAD and NAD+, oxidation reaction
Explanation:
Pyruvate dehydrogenase is a multi-enzyme complex with 5 co-enzymes and 3 apo-enzymes:
Pyruvate dehydrogenase (E1) , which uses thiamine pyrophosphate (TPP) as as co-enzymes to catalyze oxidative decarboxylation of pyruvate to hydroxyethyl-TPP.
Dihydrolipoyl transacetylase (E2): which uses lipoamide and coenzyme A as co-enzymes to catalyse the transacetylation from TPP to Lipoamide to form acetyl lipoamide.
Dihydrolipoyl dehydrogenase (E3) which uses FAD and NAD+ as co-enzymes to catalyze the oxidation of lipoamide