Chimeric mice are generated where approximately 50% of the cells in the animal are genetically MHC class I-deficient. The other 50% are deficient for the herpes virus receptor, HVEM, but do express MHC class I molecules. When these mice are infected with herpesvirus by intraperitoneal injection, a robust virus-specific CD8 T cell response is detected at day 7 post-infection in the spleens of the infected mice.
Chimeric mice are generated where approximately 50% of the cells in the animal are genetically MHC class I-deficient - Immunobiology
: a branch of biology concerned with the physiological reactions characteristic of the immune state
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A nucleic acid is made of nucleotides, and nitrogenous bases are a part of a nucleotide.
DNA is a nucleic acid. The nucleotides in DNA are made up of a sugar (deoxyribose), a phosphate group, and one nitrogenous base (which will be either adenine, guanine, cytosine, or thymine).
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It is necessary because Oxygen demands need to be reduced. This may require more aggressive support
including the use of continuous positive airway pressure (CPAP) or mechanical
ventilation. Newborns born to drug-addicted mothers exhibit hyperirritability,
exaggerated reflexes, and transient tachypnea.
Answer:
By changing a gene's instructions for making a protein, a mutation can cause the protein to malfunction or to be missing entirely. When a mutation alters a protein that plays a critical role in the body, it can disrupt normal development or cause a medical condition.
