The condition involving the development of white patches on the skin caused by the loss of melanocytes is Vitiligo.
Melanocytes is a quite differentiated cellular that produces a pigment melanin interior melanosomes. This cellular is darkish and dendritic in form. Melanin production is the basic characteristic of melanocytes.
Tyrosine is processed into melanin via the enzyme tyrosinase. chemicals that act as tyrosine analogs interact with tyrosinase or different melanin-generating enzymes, disrupt melanin production and result in the mobile strain reaction, which leads to inflammation and autoimmune destruction of melanocytes.
Vitiligo is due to the dearth of a pigment referred to as melanin in the pores and skin. Melanin is produced by using pores and skin cells referred to as melanocytes, and it gives your pores and skin its color. In vitiligo, there aren't sufficient operating melanocytes to provide sufficient melanin for your pores and skin. This reasons white patches to develop in your skin or hair.
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Small Intestine, mainly Jejunum and Ileum
This first one is both i think
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