I would say C because the <span>Renaissance was its own invented version of </span><span>humanism.
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Usually, <em>a disease is considered pandemic</em> when it crosses international borders. A disease that does not cross international borders is an epidemic. An example of a pandemic would be the Black Plague (also called the Black Death or the Bubonic Plague), which <em>killed most of the population of Western Medieval Europe.</em>
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Theodore Roosevelt was the 26th