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Dimas [21]
3 years ago
14

The effect of pH on the binding of oxygen to hemoglobin results in:

Chemistry
1 answer:
siniylev [52]3 years ago
3 0

Answer:

D. increasing protonation of β-chains His 146 with decreasing pH (i.e., higher H concentration) which stabilizes the T state conformation of Hemoglobin.

Explanation:

Human Hemoglobin is a tetrameric protein: consists of two α- and two β-subunits, and is organized as a dimer of two identical αβ dimers to form an (αβ)2 tetramer. Each subunit contains one heme group to which one O2 molecule binds reversibly. Hemoglobin principally has T low oxygen affinity state and R high oxygen affinity state, deoxyHb and fully liganded Hb respectively.

The binding of ligands such as H+, Cl- or BPG lowers the O2 affinity, in such way that affinity of hemoglobin towards oxygen O2 is decreased, when acidity of the environmental solution increases.  So, when pH decrease acidity increases, there are more H+ available who bind to His 146 in  β1 and  β2 respectively. After that, O2 is released.

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natta225 [31]
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Hope this is the answer you are looking for.
8 0
3 years ago
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If hydrofluoric acid is a stronger acid than acetic acid, which statement is most likely true?
Alchen [17]

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Explanation:

A strong acid upon dissociation gives a weak conjugate base. This can also be said as stronger is the acid, weaker will be its conjugate base or vice-versa.

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4 0
3 years ago
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Vedmedyk [2.9K]
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5 0
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How to identify coplanar molecule?
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What is the function of a lyase enzyme?
elena55 [62]

Answer:

c. To facilitate a reaction of one substrate to form two products without the use of water

Explanation:

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