"Assume that a man and a woman are phenotypically normal, but the woman is heterozygous for a pericentric inversion on chromosom
e 8. The man is karyotypically normal. What is the probability that this couple's child will inherit a duplicated or deficient chromosome 8 that results from crossing over within this pericentric inversion
Pericentric inversion results in chromosome have extra copies of some genes while some genes do not have copies. It can result in slow growth rate.
If a man is heterozygous of pericentric and a woman is heterozygous of pericentric although they do not show symptoms there is 25% chance that their offspring will have it and 50% chance of them being a carrier.
T t × T t will give TT T t T t t t
If the father is not heterozygous of it but the mother is heterozygous they have 0% chance of having it and 50% chance of being heterozygous a carrier of the disorder
2. A Mendelian trait is caused by a single gene. 3. Traits can be dominant or recessive and recur in a predictable pattern in subsequent generations. ... Autosomal Recessive Inheritance: Autosomal recessive traits can skip generations and can affect both sexes.
