Question

"Assume that a man and a woman are phenotypically normal, but the woman is heterozygous for a pericentric inversion on chromosome 8. The man is karyotypically normal. What is the probability that this couple's child will inherit a duplicated or deficient chromosome 8 that results from crossing over within this pericentric inversion

Answer 1

Answer:

Explanation:

Pericentric inversion results in chromosome have extra copies of some genes while some genes do not have copies. It can result in slow growth rate.

If a man is heterozygous of pericentric and a woman is heterozygous of pericentric although they do not show symptoms there is 25% chance that their offspring will have it and 50% chance of them being a carrier.

T t × T t will give TT T t T t t t

If the father is not heterozygous of it but the mother is heterozygous they have 0% chance of having it and 50% chance of being heterozygous a carrier of the disorder

T t × TT will give TT TT T t T t