<span>Ian Waterman was able to sense pain and temperature because his
spinothalamic pathway was intact, but could not feel touch and limb position because of damage to his
lemniscus pathway. </span>
The lateral spinothalamic tract is a sensory pathway which carries sensory information like pain and temperature to the brain, across the thalamus. Free nerve endings which are located in the peripheral tissues are sensitive to cell damage. Those are primary neurons and they pass the sensory signal. Primary neurons synapse with secondary which are located in the spinal cord (white matter). These secondary neurons will ascend through the brainstem, medulla oblongata, pons and midbrain, until synapsing in the ventroposteriorlateral (VPL) nucleus of the thalamus. From the thalamus, the information is sent to cortex (somatosensory cortex).
Posterior column-medial lemniscus pathway is ascending spinal tract, carrying sensory information to the brain (sensory pathway). It conducts localized sensations of fine touch, vibration and proprioception (position sense) from the skin and extremities (muscles) to the central nervous system (cerebral cortex).
Answer:
The correct answers are option A. "tethering proteins to the cell cortex", B. "using barriers such as tight junctions", C. "tethering proteins to the extracellular matrix", D. "forming a covalent linkage with membrane lipids", E. "tethering proteins to the surface of another cell"
Explanation:
According to the fluid-mosaic model, the components of cell membranes are in constant movement forming a barrier to avoid unwanted exterior component internalization and to avoid the loss of precious internal components. This constant movement could cause that proteins move across the plasma membrane. But, this is avoided by several mechanisms including:
A. Tethering proteins to the cell cortex. The cell cortex is a rigid structure made of actin and actomyosin. Proteins found in the plasma membrane are tethered to this structure to restrict their movement.
B. Using barriers such as tight junctions. Tight junctions are barriers found in epithelia made of claudin and occludin proteins. These barriers are impenetrable, which avoid the movement of proteins in the cell membrane.
C. Tethering proteins to the extracellular matrix. The extracellular matrix is made of several proteins and macromolecules that provide a structural and biochemical support to cells that are nearby. Proteins could be tethered to this rigid structure as well.
D. Forming a covalent linkage with membrane lipids. The proteins in the cell membrane that form a covalent linkage with membrane lipids are known as lipid-anchored proteins, or lipid-linked proteins.
E. Tethering proteins to the surface of another cell. When cell-cell communication take place it is possible that proteins in the cell membrane got tethered to the surface of the other cell.
<span>Out of the following given choices;</span>
A. Further antibody attack.
B. Phagocytosis
C. Helper T cells
D. B cells.
E. None of the above.
The answer
is B. Phagocytises is the engulfment of a particle from the external
environment, by a cell, for ingestion. This is especially critical for the
function of macrophages, which are immune cells. These macrophages have receptors
for the Fc region of the immunoglobulin on their cell membrane surface.
Missouri Compromise made provisions for federal authority in the west but prohibited the spread of human bondage.
What is Missouri Compromise?
- The Missouri Compromise Act, passed by the US Congress in 1820, admitted Missouri as the 24th state to the Union.
- Northern congressmen attempted unsuccessfully to attach amendments preventing further slaveholding after the area requested sovereignty without constraints on slavery.
- When Maine (which was once a part of Massachusetts) applied for statehood, Henry Clay brokered a deal that saw Maine admitted as a free state and Missouri admitted as a slave state.
- Slavery was subsequently outlawed in areas north of Missouri's southern boundary.
- Clay's solution highlighted the sectional divide while appearing to resolve the slavery-extension issue.
Learn more about Missouri Compromise with the help of following link:
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