Answer:
Explanation:
The switch from glutamic acid to valine in position 6 of hemoglobin (HB) forms the basis of sickle cell anemia disease pathology.
Valine is hydrophobic and it's chain is shorter than glutamic acid. The lack of the carboxylic acid and shortness of valine will result in loss of the ionic interactions formed between the glutamic acid's carboxylic group and other amino acids. A hydrophobic cavity will form in the beta sheet of HB due to the short and hydrophobic structure of valine. For these reasons, the HB molecule will be less stable and insoluble in water. The insolubility is thought to be caused by fibril formation between the valine interacting with hydrophobic pocket residues of the adjacent HB molecule. This would in turn affect binding of oxygen to HB.
The limbs of the organisms are similar because they are formed in similar ways during embryonic development and share similar arrangements.
It would be difficult to find the ideal CO2 level with a low light intensity because the plant will have a difficult time trying to survive.
<span>D. evidence that are acquired through use or disuse. Since it is believed that some parts of an organism developed through its need. For example a giraffe got its long neck becuase of reaching for a tree that could produce its food. Another example is the leg of a human which developed because of its need to walk. It was believed that the parts of the an organism did exist or did vanish depending if it was no longer used or it was necessarily needed to survive.</span>
