<h2><u><em>AIDS epidemic Russia</em></u></h2>
The number of people living with HIV in Russia now exceeds 1 million, according to official statistics. Most experts say the true figure is likely to be at least 1.5 million — around 1 percent of the total population of 146 million — because many people are unaware of their HIV-positive status.
Answer:
The answer is E. Sodium, potassium, and chloride ions but not water.
Explanation:
The thick segment of the ascending limb of the nephron loop is permeable to: sodium, potassium and chloride ions, but not water.
In this ascending branch are specific ionic channels for each of them. This ascending area of the henle handle is continued with the distal contoured tube where reabsorption and ion secretion occur again to further converate the urine.
Answer:
Joints hold the skeleton together and support movement. There are two ways to categorize joints. The first is by joint function, also referred to as range of motion. The second way to categorize joints is by the material that holds the bones of the joints together; that is an organization of joints by structure.
Explanation:
Hope this helped Mark BRAINLEST!!
Explanation:
a growing population, aging seniors, disease prevalence or incidence, medical service utilization, and service price and intensity.
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
