Full Question
Phenylketonuria (PKU) is a condition of newborns caused by an autosomal recessive allele. The incidence of PKU is one in 160,000 births in China, one in 2600 births in Turkey, and one in 119,000 births in Japan. The frequency of carriers in Turkey is
Answer:
The frequency of carriers in Turkey is 0.038%
Explanation:
Given
Incidence of PKU in China = 1 in 160,000 births
Incidence of PKU in Turkey = 1 in 2,600 births
Incidence of PKU in Japan = 1 in 119,000 births
Total = Incidence of PKU in China + Incidence of PKU in Turkey + Incidence of PKU in Japan
Total = 160,000 + 2,600 + 119,000
Total = 281,600 in the three countries
The frequency of carriers in Turkey is calculated as follows;
If there are 2600 births, there will be an incidence of 1 PKU (Phenylketonuria);
Frequency = 1/2600
Frequency = 0.0003846154
Frequency = 0.03846154%
Frequency = 0.038% --- Approximated
Hence, the frequency of carriers in Turkey is 0.038%
