Answer:
DNA vaccines consist of DNA vectors or plasmids (small double-stranded DNA rings originally derived from bacteria, but unable to cause infection) into which the genes encoding one or more immunizing proteins of the infectious agent have been inserted causing the disease to be prevented.
Explanation:
Vectors are the functional unit of naked DNA vaccines. Genes that encode the proteins of interest and are of bacterial origin are inserted into these vectors. Bacterial plasmids are circular DNA molecules that self-replicate extrachromosomally in bacteria. The genes encoded in these plasmids are under the control of promoters, almost always of viral origin. When a plasmid is introduced into the cell it translocates to the nucleus, where transcription of the transgene begins; the transcripts are then taken to the cytoplasm and translated there. The newly synthesized proteins are degraded in the proteasome to 8-10 amino acid peptides, which are transported to the endoplasmic reticulum. Peptides of high affinity with their respective MHC I molecule stabilize and enter the secretory pathway, thus reaching the cell surface, where they are coupled with the T-lymphocyte receptor (TcR) present on the surface of T lymphocytes cytotoxic drugs (CD8 +) to induce their activation.
Bellow I attached the punnet square you need. From it you can see, that the likelihood of producing an offspring with attached earlobes is 25% (ff)
Answer:
The correct answer is 7.5 ml
Explanation:
The medicine contains 100 mg in 5 ml, that means that the concentration of the active ingredient is 100 mg/5 ml= 20 mg/ml
If we divide a concentration (in mg/ml) into a mass (in mg) we obtaine a volume (in mL). Thus, in order to calculate the mililiters of medicine which contain 150 mg of the active, we have to only divide mass (150 mg) into the concentration of active ingredient as follows:
mL =
= 7.5 mL
Answer:
D.) repressor DNA-binding site mutation
Explanation:
lacl prevents the repressor polypeptide is a mutant that prevent operon from binding lactose, and thus will bind to the operator and be non-inducible.. This mutant will represses the lac operon whether lactose is present or not and the lac operon will not be expressed. It is also called“super-supperesor".
The lacI locus – One type of mutant allele of lacI (callled I-) prevents the production of a repressor polypeptide or produces a polypeptide that will not allow to bind to the operator sequence.
This is also a constitutive expresser of the lac operon because absence of repressor binding permits transcription.
Answer:
Native conformation
Explanation:
Native conformation is the correct structure or shape a protein should assume when folded, of which the protein is able to perform its operational function. Outside a proteins native conformation, or when denatured, the protein becomes unable to perform its usual main functions. The native conformation of a protein is the shape it takes in other to be functional.