Autoantibodies that contribute to the destruction of beta cells contributes to the development of type I diabetes mellitus (DM)
Explanation:
The autoantibodies produced in the cells of the islet of Langerhans in the pancreas are the main contributors of type I diabetes mellitus, which is an autoimmune-mediated disease.
DM type I is caused due to inhibition of insulin secretion by the beta cells of the pancreas. The autoantibodies are produced due to the presence of autoantigens like GAD65 which causes autoimmune pathogenesis of the pancreatic beta cells.
Along with these autoantibodies, the T-cell receptors act as mediators in the destruction of beta cells which finally results in DM.
We define health as a state of complete physical, social and mental wellbeing, and not merely the absence of disease or infirmity.
From this definition you can see that health has three dimensions – physical, mental and social – which are interrelated and influence each other greatly.
Physical health relates to the efficient functioning of the body and its systems, and includes physical capacity to perform tasks and physical fitness.
Mental health is a state of wellbeing in which an individual:
recognises their own abilitiescan cope with the normal stresses of lifecan work productively and fruitfullyis able to contribute to their community.
Social health involves being able to interact with others and participate in the community in both an independent and cooperative manner.
Some examples of how events can influence all dimensions of health:
Example 1: A 16 year old male is involved in a car accident and breaks his pelvis, rendering him unable to attend school, or play football with the local club he loves.
His physical health is affected by the damage done to his pelvic bones and a loss of fitness, which in turn has prevented him from maintaining social contact at school and football, decreasing his ability to interact with others and have good social health. His isolation may also reduce his mental health as he may feel lonely and depressed.
Example 2: A 33 year old woman develops depression.
Depression causes feelings of hopelessness, stress and loss of interest in normal activities, negatively impacting her mental health. This may decrease her desire to exercise or prepare healthy food, leading to weight gain and loss of fitness, reducing her physical health. Her depression may mean that she isn’t interested in interacting with others and participating in her community, and her moodiness puts a strain on her relationship with her husband, reducing her social health.
I would go with A because women naturally have more fat then men do for carrying children. Hope this helped.
right side:
Blood enters the heart through two large veins, the inferior and superior vena cava emptying oxygen-poor blood from the body to the right atrium.
atrium contracts, blood flows from your right atrium into your <em>right ventricle</em> through the open tricuspid valve.
ventricle contracts, blood leaves the heart through the pulmonic valve, into the <em>pulmonary artery</em> and to the lungs where it is oxygenated.
left side:
<em>pulmonary vein</em> empties oxygen-rich blood from the lungs into the <em>left atrium</em>.
contracts, blood flows from your left atrium into your <em>left ventricle </em>
ventricle contracts, blood leaves the heart through the aortic valve, into the<em> aorta </em>and to the body.
veins carry blood to the heart ( deoygenated blood)
Arteries carry blood from heart ( oxygen rich blood)
Capillaries connects them.
