Developments were made in irrigation, crop raising and breeding, building and handicrafts. Trade and commerce also flourished, and the Silk Routes became an increasingly important part of economic and cultural life, whilst coinage from this time serves as an indication of the political structure of the Kushan Empire
Answer:
A) Conquest of Persia by Alexander of Macedon.
For human cost we lose soldiers which can sisters, brothers, fathers, mothers, for economic it puts big debt because people lose jobs and lose money, and for political it can be a positive or negative output.
The area around India and the Indian Ocean.