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victus00 [196]
3 years ago
10

3TC is an antiretroviral treatment used to prevent HIV infection from becoming AIDS. After treatment with 3TC, the HIV populatio

n in a patient consists entirely of 3TC-resistant virus particles. What best explain this phenomenon? A) HIV can change its surface proteins through mutations and resist vaccines. B) The patient became re-infected with 3TC-resistant viruses after the initial exposure. C) The drug caused RNA changes to occur, creating a resistance to the once-applicable drug. D) A few drug-resistant viruses were present at the start of treatment and selective pressures increased their frequency.
Biology
1 answer:
Alexxandr [17]3 years ago
5 0

Answer:

D

Explanation:

3TC is an antiretroviral treatment used to prevent HIV infection from becoming AIDS. After treatment with 3TC, the HIV population in a patient consists entirely of 3TC-resistant virus particles. What best explain this phenomenon?

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Adenylate cyclases (ACs) are the membrane-bound glycoproteins that convert ATP to cAMP and pyrophosphate.

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Humans have 9 different AC isoforms, with AC5 and AC6 thought to be particularly important for cardiac activities.

Nitric oxide has an impact on the activity of AC6, hence the protein's nitrosylation may control how it works. However, little is known about the structural variables that affect nitrosylation in ACs and how they relate to G's.

We predict the cysteines that are prone to nitrosylation using this 3D model, and we use virtual ligand screening to find potential new AC6 ligands.

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Learn more about glycoproteins here brainly.com/question/9507947

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2 years ago
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Bond [772]

Answer:

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Explanation:

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