The Trail of Tears ended in present-day Oklahoma. This forced relocation began in Georgia and moved most of the Cherokee and other southeastern tribes to Oklahoma, which was then called Indian Territory. This relocation resulted in the deaths of many Native Americans and was clearly rooted in the racist attitudes of white Americans at that time.
Just by common sense we can rule out both C and B because neither of those make sense for this case. High population really doesn’t matter. So the most logical answer is D. Mostly Defending Familiar Territory