Answer:
When a protein is denatured, secondary and tertiary structures are altered but the peptide bonds of the primary structure between the amino acids are left intact. Since all structural levels of the protein determine its function, the protein can no longer perform its function once it has been denatured.A protein becomes denatured when its normal shape gets deformed because some of the hydrogen bonds are broken. Weak hydrogen bonds break when too much heat is applied or when they are exposed to an acid (like citric acid from lemon juice).
Helps with oxygen and stuff
In the population with a large number of individuals, the mutation would only have a small impact, while a population with only 18 individuals would result in a very large i off as the mutation would be in a greater percentage of the population.