Dementia related to vascular dementia typically has more severe memory loss then with Alzheimer’s disease?

1 answer:

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Alzheimer's disease accounts for 60 to 80 percent of cases. Vascular dementia, which occurs after a stroke, is the second most common dementia type. But there are many other conditions that can cause symptoms of dementia, including some that are reversible, such as thyroid problems and vitamin deficiencies.

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Evidence suggests that _____ may be a final common target of antidepressant treatment.

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Evidence suggests that cAMP response-element-binding protein (CREB) may be a final common target of antidepressant treatment.

Antidepressant medications work by binding to a number of monoamine neurotransmitter receptors and activating the cAMP signal transduction pathway. Chronic antidepressant therapy has been linked to the cAMP signalling system. Increases in cAMP cause the cAMP response element-binding protein(CREB) to be phosphorylated more frequently via increased receptor adenylate cyclase activity .

CREB mediates transcriptional responses to increased cAMP levels by attaching to cAMP response element (CRE) sites.In order to prevent recurring episodes, treatment for depression should maintain therapeutic efficacy while also addressing behavioural symptoms and indicators of the illness. One important modulator of the transcriptional effects of antidepressants may be CREB.

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The answer is: "obsessive-compulsive disorder (OCD)" .
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