The answer is C & E
Fatigue as well as Enlarged lymph nodes
Answer:
Mutations in the HBB (beta-globin) protein causes symptoms of sickle cell disease.
The situation that a new technology would be most likely to cause change in existing theory about cell is : D. The technology allows detection of a substance that could not be detected previously
Cell is incredibly small and we still hasn't 100% figured out their perfect mechanism yet. New technology might found the new substance that alter the cell's theory as a whole
hope this helps
Some of the main causes are plant growth and ice wedging.