Yes, rural areas should be concerned about contagious diseases since they affect rural healthcare systems and citizens' quality of life, mortality, and healthcare expenses.
Though urban areas offer better living circumstances than rural ones like improved housing, sanitization, ventilation, and social services, but they are potential hotspots for the fast transmission of infectious illnesses due to the population density and frequent contact between residents.
On the other hand, rural areas may not have a high population density, yet they should still be concerned about contagious diseases since they lack the facilities and better healthcare that urban areas have.
As a result, both urban and rural areas should be concerned about the spread of infectious illnesses.
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Dementia and Delirium are two somewhat broad biological phenomenon that are biological causes of mental illness. These interfere with biological processes with the brain. If we wish to be more specific, Cancers, Alzheimer and Parkinson's Disease can affect the brain by pressing on important aspects (Brain Cancer's) and/or cause progressive degeneration (Alzheimer and Parkinson's)