Answer:
Genetic mapping for unequivocal identification of the potentially causative mutation
Explanation:
Galactosemia is a genetic disorder caused by mutations in the Galactose-1-phosphate uridylyltransferase (GALT) gene, which encodes an enzyme involved in the metabolism of galactose. Gene mapping is a technique widely used in genetics to identify the position of one locus a chromosome by using molecular markers to estimate genetic distances. Genetic mapping provides useful evidence in order to identify when a disease that is transmitted from parent to offspring can be associated with one or more genes and then determine which gene/s is/are responsible for this condition.
There is less diversity hope this helps
Answer:
The fraction of heterozygous individuals in the population is 32/100 that equals 0.32 which is the genotipic proportion for these endividuals.
Explanation:
According to Hardy-Weinberg, the allelic frequencies in a locus are represented as p and q, referring to the alleles. The genotypic frequencies after one generation are p² (Homozygous for allele p), 2pq (Heterozygous), q² (Homozygous for the allele q). Populations in H-W equilibrium will get the same allelic frequencies generation after generation. The sum of these allelic frequencies equals 1, this is p + q = 1.
In the exposed example, the r-6 allelic frequency is 0,2. This means that if r-6=0.2, then the other allele frequency (R) is=0.8, and the sum of both the allelic frequencies equals one. This is:
p + q = 1
r-6 + R = 1
0.2 + 0.8 = 1
Then, the genotypic proportion for the homozygous individuals RR is 0.8 ² = 0.64
The genotypic proportion for the homozygous individuals r-6r-6 is 0.2² = 0.04
And the genotypic proportion for heterozygous individuals Rr-6 is 2xRxr-6 = 2 x 0.8 x 0.2 = 0.32
B , d and e. I believe that is correct
