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3 years ago

Explain how XY mice with a duplication of chromosome 1 develop ovaries and a female phenotype.

Biology

1 answer:

Dahasolnce [82]3 years ago

3 0

Answer:

Duplication of the Dax1 is associated to equivocal sex determination on how XY mice develop ovaries and a female phenotype which comes from strong expression of the homologous gene (Ahch) in the first stages of gonadal (and adrenal) differentiation.

Explanation:

Dose-Sensitive Sex Reversal Locus on Chromosome X, Gene 1 , DAX1∗ (officially, nuclear receptor subfamily 0, group B, member 1; NR0B1) is a member of the nuclear hormone receptor superfamily of transcription factors that functions primarily as a transcriptional repressor.

Duplication of the DAX1/NROB1 locus is associated with male-to-female sex reversal, that is ambiguous external genital differentiation ranges.

One X chromosome and one Y chromosome in each diploid cell of their bodies differencite males from females, who typically have two X chromosomes but XX males that are SRY-positive have two X chromosomes, with one of them containing genetic material from the Y chromosome, making them phenotypically male but genetically female.

DAX1 protein may be directly or indirectly involved in gonadal regulation of hypothalamic-pituitary function.

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3 years ago

The brain volumes (cm cubed) of 20 brains have a mean of 1116.2 cm cubed and a standard deviation of 127.7 cm cubed. Use the g

Shkiper50 [21]

Answer:

Yes

Explanation:

Range rule of thumb predicts the Range to be a multiple of 4 of the standard deviation or to be four times the standard deviation. Making the usual values equal to 2 standard deviations distanct of the mean of the data distribution.

In a given distribution with mean and standard deviation that is obtained, the usual values in mean (as seen in the attached image).

2*standard deviation and mean + 2*standard deviation.

If the data point is not up to the mean

- 2* standard deviation is taken to be significantly low.

If the data point is more than the mean

+ 2*standard deviation is taken to be significantly high.

Let's take the xbar to be the mean and s as standard deviaiton

Given,

mean, xbar = 1116.2

standard deviation, s =127.7

The range rule of thumb shows that the usual values are within 2 standard deviations from the mean

Lower boundary

= xbar - 2s

= 1116.2 - 2(127.7)

= 860.8

Upper boundary

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