Question

Securin is a cytoplasmic protein that binds to separase, an enzyme that degrades cohesin. When separase is bound to securin, separase is inactive. When separase is released, it immediately becomes active. Securin and separase remain attached to each other as long as securin is phosphorylated. Based on the role of securin, it must become dephosphorylated just prior to
metaphase.

anaphase.

prometaphase.

prophase.

telophase.

cytokinesis.

Answer 1

Answer:

Anaphase.

Explanation:

Two main process of cell division are mitosis and meiosis. The regulation of the cell cycle is maintained by the regulation of cyclins, cdks and important protein factors.

Securin and separase are important proteins that allow the transition of one phase of the cell cycle to the another phase. The securin helps in the separation of the chromosome and sister chromatid that occurs in anaphase. Hence, dephosphorylation must occur prior to anaphase.

Thus, the correct answer is option (2).