Answer:
Explanation:
The switch from glutamic acid to valine in position 6 of hemoglobin (HB) forms the basis of sickle cell anemia disease pathology.
Valine is hydrophobic and it's chain is shorter than glutamic acid. The lack of the carboxylic acid and shortness of valine will result in loss of the ionic interactions formed between the glutamic acid's carboxylic group and other amino acids. A hydrophobic cavity will form in the beta sheet of HB due to the short and hydrophobic structure of valine. For these reasons, the HB molecule will be less stable and insoluble in water. The insolubility is thought to be caused by fibril formation between the valine interacting with hydrophobic pocket residues of the adjacent HB molecule. This would in turn affect binding of oxygen to HB.
A. nucleus
the nucleolus in the inner part of the nucleus, and chromosomes and genes are found within the nucleolus
When a wave has a height of 5 feet and a wavelength of 15 feet then it has a wave base of 7.5 feet. Wave base is equal to the half of the wavelength so if you consider your wavelength to be 15 feet then it is divided into 2 that would give you answer of 7.5 feet.
I Think The answer is a I hope it helps My friend
