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maw [93]
4 years ago
11

Which of the statements regarding the cell cycle is true? Group of answer choices It is regulated by cyclins and CDKs. Different

levels of cyclins are observed at different cell cycle stages. It can be "paused" by the action of p53. It has many major cell cycle checkpoints. All of these choices are correct.
Biology
1 answer:
MA_775_DIABLO [31]4 years ago
7 0

Answer:

All of these choices are correct.

Explanation:

Cell cycle is the process of growth and division of cell. It comprises of interphase and mitosis. In interphase the cell grows, replicates its genomic content and prepares itself for division. In mitosis the division occurs.

Cell cycle is controlled by a group of kinases called as Cyclin dependent Kinases (CDKs). They act by phosphorylating their substrates. They are of various types like Cdk1, Cdk2, Cdk4 etc. They become active when they bind to a regulatory protein called cyclin. They are also of various types like Cyclin A, Cyclin B, Cyclin C etc. Level of cyclin and corresponding CDK increases and decreases according to the stage of cell cycle. For example in S phase of cell cycle concentration of cyclin A and E shoots up. CDK2 is able to bind to these cyclin molecules and hence it becomes active.

Cell cycle has major checkpoints where the condition of cell is analysed before it proceeds to the next stage of cycle. If any abnormality is detected, repair mechanism is activated or the cell is killed. Checkpoints do not allow cell cycle to proceed in damaged cells.

p53 is a tumor suppressor protein which can halt cell cycle when it detects some abnormality in cell. It usually acts in G1/S checkpoint (before the DNA replication starts in cell) and G2/M checkpoint (before the cell division begins). Hence, all of the above statements are true.

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xenn [34]

Answer:

A mutation in <u>DNA </u>results in a change in <u>RNA </u>that sometimes produces a <u>protein </u>with altered structure and function.

Explanation:

DNA is the hereditary material which causes gene expression in our body by producing protein. The type of protein which is produced by DNA totally depends upon the sequence of nucleotides in the DNA. But, DNA molecule does not produce protein directly. Initially it produces RNA (mRNA, tRNA, rRNA) by the process of transcription, the nucleotides in the RNA are complimentary to those in DNA. In short, the message regarding the structure and composition of the type protein to be produced by DNA is first decoded from DNA in the form of RNA. These RNA molecules then synthesize the protein as per the instructions from DNA by the process of translation.

But, in case a mutation occurs in the DNA which causes a change in it's nucleotide/nucleotides, the protein which will be produced will be different in the structure and function than the protein which was supposed to be synthesized. It happens because, a triplet of nucletiodes in the DNA and hence RNA specifies a particular type of amino acid and several amino acids are joined in a long chain to form polypeptide which ultimately forms protein. But, if any nucleotide in the triplet is changed due to mutation it may change the amino acid and if amino acid will change the protein will also get altered.

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Answer:

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