<h2>b) option is correct </h2>
Explanation:
- Some bacterial toxins cause disease by altering the activity of G protein, cholera toxin is one of them
- Cholera toxin catalyse ADP ribosylation of Gs and blocks GTPase activity thus Gs GTP become permanently active
- Constitutive activation of Gs protein continuously induce adenylyl cyclase, cytosolic cAMP level rises that leads to activation of protein kinase A (pKA)
- Activated pKA catalyse phosphorylation of two transmembrane proteins of intestinal epithelial cells:
- CFTR cause excessive outflow of Cl- ion and Na+ H+ exchange cause efflux of Na+ ion, both enters in gut and form Na+ Cl-
- Na+Cl- leads to outflow of water from the gut, resulting in diarrhea and dehydration and this condition may cause death of organisms due to loss of water and ions
The correct answer is True.
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Answer:
The simplest mechanism by which molecules can cross the plasma membrane is passive diffusion. Passive diffusion is thus a nonselective process by which any molecule able to dissolve in the phospholipid bilayer is able to cross the plasma membrane and equilibrate between the inside and outside of the cell.
Hello There!
The sensory nervous system transmits information from receptors to the CNS, while the motor nervous system transmits information from the CNS to the rest of the body.
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- Hannah ❤
