Question

Mutations that change the nucleotide sequence without changing the amino acid sequence are

Answer 1

Mutations that change the nucleotide sequence without changing the amino acid sequence are synonymous mutations.

Synonymous mutations or substitution are those that change a codon with another codon that codes for the same amino acid. As a result, the synthesized amino acid sequence is not modified. Synonymous mutations usually don’t result in any phenotypic effects, so they are called silent.