D is the best answer because gas exchange takes place in our lungs. Our lungs have alveoli which have a network of tiny blood vessels called capillaries, here the O2 diffuses the capillary wall to enter the bloodstream, and similarly CO2 diffuses out and we exhale it our from our lungs.
Fructose 1,6-bisphosphatase, on the other hand, is inhibited by AMP and activated by citrate. A high level of AMP indicates that the energy charge is low and signals the need for ATP generation.