Hypotension will cause the interstitial fluid hydrostatic pressure to increase and capillary hydrostatic pressure to decrease. The net filtration pressure will be reduced favoring the absorption .
Explanation:
Hypotension refers to reduced blood pressure. Decrease in blood pressure results in reduced filtration pressure on capillary walls. This reduces the filtration of water and solutes into the tissue fluid but will favor the movement of water from tissue to blood. So we can say that net filtration pressure will be reduced.
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The answer is
B........................................
Answer : The dissociation constant of the PFK‑inhibitor complex is, 5 µM
Explanation :
The expression for reversible competitive inhibition when apparent Km affected by addition of the inhibitor is:
![K_m_a=K_m[1+\frac{I}{K_i}]](https://tex.z-dn.net/?f=K_m_a%3DK_m%5B1%2B%5Cfrac%7BI%7D%7BK_i%7D%5D)
where,
= apparent value = 52 µM
= Michaelis–Menten constant = 40 µM
I = inhibitor concentration = 1.5 µM
= dissociation constant of the PFK‑inhibitor complex
Now put all the given values in the above formula, we get:
![52\mu M=40\mu M[1+\frac{1.5\mu M}{K_i}]](https://tex.z-dn.net/?f=52%5Cmu%20M%3D40%5Cmu%20M%5B1%2B%5Cfrac%7B1.5%5Cmu%20M%7D%7BK_i%7D%5D)
Therefore, the dissociation constant of the PFK‑inhibitor complex is, 5 µM
