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Andrews [41]
3 years ago
13

How does Thermally Sensitive Liposomes Work?

Biology
1 answer:
Virty [35]3 years ago
7 0

Answer:

Thermosensitive liposomes (TSL) are promising tools used to deliver drugs to targeted region when local hyperthermia is applied (∼40–42°C) which triggers the membrane phase transformation from a solid gel-like state to a highly permeable liquid state. Selective lipid components have been used to in TSL formulations to increase plasma stability before hyperthermia and speed drug release rate after. Two generations of TSL technology have been developed. The traditional thermal sensitive liposomes (TTSL) have utilized DPPC and DSPC as a combination. The second generation, lysolipid thermally sensitive liposomes (LTSL) technology, has been developed with incorporation of lysolipids that form stabilized defects at phase transition temperature. LTSL maintains certain favorable attributes:

High percentage of lysolipids incorporation;

Minimum leakage for therapeutical drugs encapsulation;

Ultrafast drug release upon heating (3.5 times enhanced compared to TTSL). For example, ThermoDox, a commonly used LTSL drug for cancer, has been reported to release 100% of the encapsulated doxorubicin within 30s;

First and most successful formulation for intravascular drug release.

Explanation:

https://www.creative-biostructure.com/Lysolipid-Thermally-Sensitive-Liposomes-Production-612.htm

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Answer:

When a male pig from a line of true-breeding (homozygous) black, solid-hooved pigs was crossed to a female from a breed (homozygous) of red, cloven-hooved pigs, their several progeny all looked alike with regard to color and hooves. These progeny were all mated to members of the same breed as their red, cloven-hooved mother pig. The offspring from this final cross were: 11 black, cloven-hooved; 8 black, solid-hooved; 14 red, cloven-hooved; and 10 red, solid-hooved. For each of these two genes (coat color and hoof type) determine which allele is the dominant one. Explain your reasoning. What were the phenotypes of the progeny produced by the first mating in this problem.

3 0
3 years ago
Name three gene mutations
lesya692 [45]

Answer:

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Explanation:

4 0
3 years ago
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-Dominant- [34]

Answer:

Option B, It was made in stars that lived before the solar system formed.

Explanation:

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3 0
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4vir4ik [10]
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