icric acid is a able to denature proteins by altering the tertiary configuration of proteins. Meaning that it is capable for picric acid to precipitate protein particulates by altering the state of either H-bonding and vander-waals dispersion forces, this eventually renders the hydrophobic end of the protein in its outer stratum and the hydrophilic end in the center which is generally binded to picric acid. This again as a conclusion makes an insoluble precipitate out of your denatured protein. This ppt'n. in a sense clogs the pathway for any pathogen, or interstitial fluid of your body to exit the wound or for the pathogen to enter. This again helps your fibrinogens fight against the progress of infection and your body to sustain good amount of monocytes in the infected area.
The conflict arose because the US citizens wanted to spread towards the western shores and pushed the Natives out of their land and forced them to migrate. The conflict didn't get resolved since there was war and fighting because many didn't want to go, but in the end they were placed in reservations.
They helped new Mexico become a state