Question

You are analyzing a human pedigree for a new disease and discover that the disease occurs with the same frequency in both sexes and that 25% of the children from two unaffected heterozygous parents have the disease. This disease is displaying ____ inheritance.

Answer 1

The disease displays autosomal recessive inheritance.

Explanation:

Autosomal recessive Inheritance is a way in which the disorder/trait (mutation in a gene) present in the 22 non-sex chromosomes are passed through the family Two healthy parents who are unaffected but have “one mutated gene (recessive)” and “one normal gene (dominant)” are the carriers of mutated gene for an “autosomal recessive disorder”.  

The possibility that the child gets the disorder in each pregnancy is 25%. The possibility that the unaffected child is a carrier of the disorder is 50% and that a child is not having the disorder and is not a carrier is 25%.