In 1923 when Hubble spotted a Cepheid variable star in what was called Andromoda Nebula and he was able to show that Andromoda was a million light years away ,which meant that it obviously wasn’t just a cloud of gas but a whole galaxy itself.And his discovery led to him becoming the most famous astronomer in the world just overnight ,because he brought us the fact that the “world” was bigger than we thought it was
This is possible because of the length of the protein. It is always possible to add more amino acids and synthesize new protein and every new addition increases the number of possibilities drastically.