All living organisms need carbohydrates for their cellular functions. When we consume carbohydrates, our bodies break down glucose in the mitochondria to make ATP. If your mitochondria stopped working you wouldn’t be able to convert the food you eat into ATP for cellular functions. All the cells in your body require a constant supply of energy. Without ATP, you will quickly experience fatigue. Not long after that your bodily systems will begin to shut down and you will die, because cells can’t function without energy.
If your mitochondria fails then it will be extremely hard to covert the food into ATP. For cells that require a lot of energy like your muscles , the lack of ATP will cause you to start to fatigue. In extreme cases, infants die in the first year because no cell can work without energy.