I would tell him that his health problems are completely confidential and that I would not tell his wife. If the wife asked me, I would say to talk to your husband he will explain everything.
Men have a greater risk of heart attack then women do, and men have attacks earlier in life.
The overload princiole could make this workout more challenging as this is a full body workout and the point of overload is to push ur body until you cant do anymore which will cause you to achieve strength and muscle mass faster than small workouts. this specifically is good because its a full body workout and you will push your body to the best of its abilities. Hope this helped !!