1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Viktor [21]
3 years ago
14

A number of mutations have been described in the G protein Ras that have profound effects on its activity. For example, some mut

ations greatly increase the affinity of the G protein for GDP, making it very difficult for GDP to be exchanged for GTP. Other mutations prevent the GTPase activity of Ras, preventing it from causing the hydrolysis of GTP to GDP. Which of the scenarios would result in a persisting proliferation response to growth factor receptor activation after the ligand is no longer binding to its receptor kinase? a mutation that blocks the exchange of GDP with GTP a mutation that blocks the GTPase activity of Ras Both a mutation that blocks the GTPase activity of Ras and a mutation that blocks the exchange of GDP with GTP would cause the response to persist. Neither a mutation that blocks the GTPase activity of Ras nor a mutation that blocks the exchange of GDP with GTP would cause the response to persist.
Biology
1 answer:
gladu [14]3 years ago
6 0

Answer:

a mutation that blocks the GTPase activity of Ras

Explanation:

A G protein in inactive state is GDP bound but as soon as a guanine exchange factor (GEF) exchanges it with GTP it gets activated which means that in GTP bound state it is active. G - protein has endogenous GTPase activity. Upon interaction of GAP, the GTPase activity of this protein is exhibited. When GAP is present, hydrolysis of GTP into GDP occurs which leads to inactivation of G protein. A mutation which will block GTPase activity of Ras will therefore result in constitutive active signaling even in the absence of ligand binding to it's receptor. In such scenario, GTP will not be hydrolyzed into GDP so signaling will be up-regulated.

You might be interested in
Which parts of photosynthesis occur in the thylakoid membranes of the grana?.
abruzzese [7]

Answer:

The light-dependent reactions take place in the thylakoid membranes in the granum (stack of thylakoids), within the chloroplast. Figure: The two stages of photosynthesis: Photosynthesis takes place in two stages: light-dependent reactions and the Calvin cycle (light-independent reactions).

Explanation:

Each stack is called a granum (the plural is grana) which is suspended in a fluid called stroma. The light-dependent reactions occur in the grana; the light-independent reactions take place in the stroma of the chloroplasts.

6 0
2 years ago
The expected phenotypic ratio of a dihybrid cross is
Arlecino [84]

Answer:9:3:3:1

Explanation: Just took the test!

3 0
2 years ago
Read 2 more answers
What substances are returned to the blood before it leaves the kidneys?​
bekas [8.4K]

Answer:

The process is called reabsorption.

The substances that are returned are glucose, amino acids, water and salt. Hope this helped

6 0
3 years ago
Hey can anyone help me with this?
jarptica [38.1K]
Yes , i would help you but the photo isn't clear . :(
4 0
3 years ago
Which processes would cause an animal cell to burst if it were placed in distilled water
Agata [3.3K]

Answer:

Pag answer og inyooooooooooooooo

3 0
3 years ago
Read 2 more answers
Other questions:
  • Help quick!! Give three examples of protist
    6·1 answer
  • one proposed project to help restore Louisiana wetlands is to backfill canals that were built for access to and transportation o
    12·1 answer
  • Which of the following in NOT hydrophobic?
    10·1 answer
  • Which of the following is the correct definition of nuclear energy?
    8·1 answer
  • What trait of chloroplasts leads scientists to believe they were once independent microbes?
    15·1 answer
  • Do you like yours sister
    8·2 answers
  • Why would archaea that grow in extreme environments be more intensively studied than those that do not?
    7·1 answer
  • List the order in which Consumers arrive to your new ecosystem
    13·1 answer
  • When do babies' eye colors change?
    8·2 answers
  • What factors do you think have contributed to the growing wolf populations?
    9·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!