Monogenetic disorders are caused by a mutation in a single gene. The mutation may be present on one or both chromosomes (one chromosome inherited from each parent). Examples of monogenic disorders are: sickle cell disease, cystic fibrosis, polycystic kidney disease, and Tay-Sachs disease.
Highest risk body fluid would be blood because it has high nutritional value and pathogen is multiplying on there. Most pathogen will be transmitted by blood.
Droplet from cough also highly contagious since it easily contacts with any part of the body. Inhalation also makes the infection easier since it contacts mucosa.
Vaginal secretion and seminal fluid can transmit many virus but it depends on how many virus in the blood.
Saliva is composed by water and enzyme so it's low risk on virus spread. But it's on the mouth(which wasn't sterile) so it can be contaminated by various things.
In normal condition urine and spinal fluid is sterile, but in a case of infection, it can be contaminated.
Sweat is mostly water and salt so it's safe.
By revolving the around the addition of a nucleotide with the incorrect base.
