A colonoscopy is a screening test for colon cancer, recommended as a routine test for adults over age 50. A new study provides t
he best evidence yet that this test saves lives. The proportion of people with colon polyps expected to die from colon cancer is 0.01. A sample of 2602 people who had polyps removed during a colonoscopy were followed for 20 years, and 12 of them died from colon cancer. Does this provide evidence that the proportion of people who die from colon cancer after having polyps removed in a colonoscopy is significantly less than the expected proportion (without a colonoscopy) of 0.01? What are the null and alternative hypotheses?
The null hypothesis (H0) tries to show that no significant variation exists between variables or that a single variable is no different than its mean. While an alternative Hypothesis (Ha) attempt to prove that a new theory is true rather than the old one. That a variable is significantly different from the mean.
For the case above;
The null hypothesis is that the proportion of people with colon polyps expected to die from colon cancer remains 0.01 with or without colonoscopy.
H0: p = 0.01
The alternative hypothesis is that the proportion of people who die from colon cancer after having polyps removed in a colonoscopy is significantly less than the expected proportion (without a colonoscopy) of 0.01.