Prohibition would have failed regardless of the atmosphere, because people like to drink alcohol. The permisive attitude of the times (mild compared to today) meant there was little social stigma attached to those who ignored prohibition. People finally came to realize that all they did was stregnthen the mob and lose tax revenues with Prohibition.
The major way in which border areas of the west were affected by the mixture of people is that a plethora of immigrants from all over the world wanted to expand to the west in order to settle--meaning that people from all backgrounds often fought over land and job opportunities.
The late 19th-century United States is probably best known for the vast expansion of its industrial plant and output. At the heart of these huge increases was the mass production of goods by machines. This process was first introduced and perfected by British textile manufacturers.