Tissue damage activates nociceptors or pain receptors in the skin. A signal is sent to the peripheral nerve to the spinal cord where neurotransmitters or chemical messengers are released. It activates other nerves to pass signal to the brain. The signals are relayed to the somatosensory cortex for sensation, frontal cortex for thinking and limbic system for emotional response.
According to DNA methylated bases, the cell alteration linked to differential cytosine methylation on disease patients' DNA is referred to as an epigenetic modification.
<h3>What do you understand by epigenetics?</h3>
The study of epigenetics, a branch of genetics that focuses on how various chemical alterations to the DNA nucleotide sequence and associated chromatin proteins (histones) may change the expression of particular genes, is crucial for understanding disease states and developmental pathways.
The epigenetic changes, which control gene expression in specialized eukaryotic cells, include DNA methylation organized on CpG islets (cytosine-rich areas), acetylation and/or methylation of histones, non-coding RNA pathways, etc.
The study of how chemical groups added to DNA and/or associated chromatin proteins may change gene expression and hence affect the status and progression of disease is known as epigenetics, according to the findings presented here.
To know more about epigenetics, refer
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Mutation caused by external relationships. If you were to have an isolated population, they would be forced to have incest to survive. You need genetic variation from other creatures.
Potatoes do not swell when it rains. When it rains the potatoes absorbs water mostly through its roots.
