The longest day of the year isn't the hottest day of the year because the phenomenon of the hottest weather following the summer solstice by a month or two is called the lag of seasons.
Answer:
Reproductive isolation refers to the inability of an organism or species to breed successfully with other organism or species.
It may arise from various factors such as:
- Geographical isolation such as river, mountain, etc
- Behavioral changes such as mating time or season, mating rituals, mating location etc.
- Physiological differences such as change in shape of sex organs which causes lack of fit between copulatory organs.
- Genetic differences.
Reproductive and geographical isolations between two populations (of same species) inhibit the flow of genes among them. Slowly, these isolations increase the variations in the gene pools of the two populations.
These genetic variations keep on increasing with time. In addition, as an adaptation to their surrounding or habitat the two populations would develop different behavioral and physiological changes
With time, these differences will increase up to such an extent that the two populations would not be able breed with each other. Hence, it would lead to the evolution of one or both the populations into new species.
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p53 protein is involved in control of cell cycle, which explains it role in tumor/ cancer suppressor